Invention Grant
- Patent Title: Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
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Application No.: US14877914Application Date: 2015-10-07
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Publication No.: US09701639B2Publication Date: 2017-07-11
- Inventor: Mark Strohmeier , John Caesar, Jr. , Patrick Raymond Connelly , Majed Fawaz , Eduard Luss-Lusis , Brian McClain , Ales Medek , Hai Miao , Kwame Wiredu Nti-Addae , Ping Yin , Yuegang Zhang
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C07D215/56
- IPC: C07D215/56 ; A61K31/225 ; A61K31/47 ; A61K45/06 ; C07C69/34
Abstract:
The present disclosure relates to co-crystals comprising N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and a co-former and methods for their preparation. The present disclosure further relates to pharmaceutical compositions comprising the co-crystal forms, as well as methods of treatment therewith and kits.
Public/Granted literature
- US20160096807A1 CO-CRYSTALS OF MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Public/Granted day:2016-04-07
Information query
