Invention Grant
- Patent Title: Methods and products for in vitro diagnosis, in vitro prognosis and the development of drugs against invasive carcinomas
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Application No.: US14237682Application Date: 2012-08-08
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Publication No.: US09702879B2Publication Date: 2017-07-11
- Inventor: Luis Barneo Serra , Carmen Garcia Pravia , Juan Ramon De Los Toyos Gonzalez , Marcos Garcia Ocana , Jose Fernando Vazquez Villa , Nelson Fuentes Martinez , Jokin Del Amo Iribarren , Laureano Simon Buela
- Applicant: Luis Barneo Serra , Carmen Garcia Pravia , Juan Ramon De Los Toyos Gonzalez , Marcos Garcia Ocana , Jose Fernando Vazquez Villa , Nelson Fuentes Martinez , Jokin Del Amo Iribarren , Laureano Simon Buela
- Applicant Address: ES Vizcaya
- Assignee: Oncomatryx Biopharma, S.L.
- Current Assignee: Oncomatryx Biopharma, S.L.
- Current Assignee Address: ES Vizcaya
- Agency: Greer, Burns & Crain, Ltd.
- Priority: ES201131374 20110809
- International Application: PCT/ES2012/070616 WO 20120808
- International Announcement: WO2013/021088 WO 20130214
- Main IPC: G01N33/573
- IPC: G01N33/573 ; G01N33/574 ; C07K16/18 ; C07K16/30 ; G01N33/50 ; G01N33/68 ; C12Q1/68
Abstract:
The present invention relates to in vitro methods and products for detecting the presence of an invasive carcinoma in an individual, for determining and/or predicting the stage and/or invasiveness of said carcinoma in an individual, or for monitoring the effect of the therapy administered to an individual who has said carcinoma based on col11a1 gene and proCOL11A1 protein expression. The invention also relates to the search for, identification, development and evaluation of the efficacy of compounds for therapy for said carcinoma, for the purpose of developing new medicinal products. The invention also relates to agents inhibiting proCOL11A1 protein expression and/or activity, and/or the effects of this expression.
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