A computer peripheral device includes a housing, and at least one multi-directional key-wheel. The multi-directional key-wheel is rotatably arranged along an axis in an abreast manner in the housing, and has a part exposed outside the housing. Each multi-directional key-wheel is polygon-shaped and has a plurality of pressing surfaces. Each pressing surface is equipped with at least one button. At least two pressing surfaces of one multi-directional key-wheel have a different quantity of buttons. Thus, the present invention can provide different button arrangement modes by exposing a different one of the pressing surfaces of the multi-directional key-wheel outside the housing. The button arrangement modes can also have a different quantity and arrangement manner of the keys.