Invention Grant
- Patent Title: (bis)urea and (bis)thiourea compounds as epigenic modulators of lysine-specific demethylase 1 and methods of treating disorders
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Application No.: US13391247Application Date: 2010-08-18
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Publication No.: US09708255B2Publication Date: 2017-07-18
- Inventor: Robert A. Casero , Patrick M. Woster
- Applicant: Robert A. Casero , Patrick M. Woster
- Applicant Address: US MD Glen Arm US SC Charleston
- Assignee: Robert A. Casero,Patrick M. Woster
- Current Assignee: Robert A. Casero,Patrick M. Woster
- Current Assignee Address: US MD Glen Arm US SC Charleston
- Agency: Burns & Levinson, LLP
- Agent Daniel W. Clarke
- International Application: PCT/US2010/045903 WO 20100818
- International Announcement: WO2011/022489 WO 20110224
- Main IPC: C07C275/00
- IPC: C07C275/00 ; C07C335/00 ; A61K31/17 ; C07C335/08 ; A61K31/155 ; A61K45/06 ; C07C275/14 ; C07C275/24 ; C07C275/28 ; C07C335/12
Abstract:
The invention provides for novel (bis)urea and (bis)thiourea compounds which are inhibitors of lysine-specific demethylase 1 (LSD1). Such compounds may be used to treat disorders, including cancer.
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