Invention Grant
- Patent Title: Aryl methyl benzoquinazolinone M1 receptor positive allosteric modulators
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Application No.: US14828216Application Date: 2015-08-17
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Publication No.: US09708273B2Publication Date: 2017-07-18
- Inventor: Scott D. Kuduk , Douglas C. Beshore , Christina Ng DiMarco , Thomas J. Greshock
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Sylvia A. Ayler; John C. Todaro
- Main IPC: A61K31/505
- IPC: A61K31/505 ; C07D239/70 ; C07D239/88 ; C07D401/06 ; C07D401/14 ; C07D403/04 ; C07D471/04 ; C07D401/04 ; C07D405/14 ; C07D409/14 ; C07D519/00 ; C07C53/10 ; C07C53/21 ; C07C57/15
Abstract:
The present invention is directed to benzoquinazilinone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
Public/Granted literature
- US20160229813A1 ARYL METHYL BENZOQUINAZOLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS Public/Granted day:2016-08-11
Information query
