Invention Grant
- Patent Title: Salt polymorph of thioxanthene-9-ylidene-1-methyl piperidine acid addition salts as antimigraine compounds
-
Application No.: US14765176Application Date: 2014-01-31
-
Publication No.: US09708304B2Publication Date: 2017-07-18
- Inventor: Beate Schmitz , Hermann Luebbert
- Applicant: BIOFRONTERA BIOSCIENCE GMBH
- Applicant Address: DE Leverkusen
- Assignee: Biofrontera Bioscience GmbH
- Current Assignee: Biofrontera Bioscience GmbH
- Current Assignee Address: DE Leverkusen
- Agency: Barnes & Thornburg LLP
- Priority: WOPCT/EP2013/052060 20130201
- International Application: PCT/EP2014/051863 WO 20140131
- International Announcement: WO2014/118307 WO 20140807
- Main IPC: C07D211/00
- IPC: C07D211/00 ; C07D295/00 ; C07D409/00 ; C07D411/00 ; C07D417/00 ; C07D419/00 ; A61K31/445 ; C07D409/04
Abstract:
The present invention relates to novel crystal forms of 4-(6-ethoxy-1-methoxy-thioxanthene-9-ylidene)-1-methyl piperidine salts and 4-(6-ethoxy-1-hydroxy-thioxanthene-9-ylidene)-1-methyl piperidine salts; especially to novel crystal forms of 4-(6-ethoxy-1-methoxy-thioxanthene-9-ylidene)-1-methyl piperidine hydrochloride and 4-(6-ethoxy-1-hydroxy-thioxanthene-9-ylidene)-1-methyl piperidine hydrochloride as well as to the use of these salts for preventing or treating migraine or pulmonary hypertension.
Public/Granted literature
Information query
