Invention Grant
- Patent Title: Spiro-lactam NMDA receptor modulators and uses thereof
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Application No.: US14764426Application Date: 2014-01-29
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Publication No.: US09708335B2Publication Date: 2017-07-18
- Inventor: John A. Lowe, III , M. Amin Khan
- Applicant: Naurex, Inc.
- Applicant Address: US IL Evanston
- Assignee: Apytinyx Inc.
- Current Assignee: Apytinyx Inc.
- Current Assignee Address: US IL Evanston
- Agency: Goodwin Procter LLP
- International Application: PCT/US2014/013639 WO 20140129
- International Announcement: WO2014/120800 WO 20140807
- Main IPC: C07D487/10
- IPC: C07D487/10
Abstract:
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
Public/Granted literature
- US20150368254A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF Public/Granted day:2015-12-24
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