Invention Grant
- Patent Title: Aromatic heterocyclylamine derivative having TRPV4-inhibiting activity
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Application No.: US15076728Application Date: 2016-03-22
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Publication No.: US09708338B2Publication Date: 2017-07-18
- Inventor: Akira Yukimasa , Naoki Tsuno , Motohiro Fujiu , Hiroki Yamaguchi , Hiromi Kudo , Tatsuhiko Ueno , Yusuke Ichihashi , Takatsugu Inoue , Shinji Suzuki
- Applicant: Shionogi & Co., Ltd.
- Applicant Address: JP Osaka
- Assignee: SHIONOGI & CO., LTD.
- Current Assignee: SHIONOGI & CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2013-198310 20130925; JP2014-112826 20140530
- Main IPC: A61K31/443
- IPC: A61K31/443 ; A61K31/4436 ; A61K31/4439 ; A61K31/496 ; A61K31/506 ; C07D401/14 ; C07D413/14 ; C07D417/14 ; C07D471/08 ; C07D498/08 ; C07D513/08 ; C07D491/08 ; C07D491/107 ; C07D471/04 ; C07D487/04 ; C07D491/10 ; C07D498/10

Abstract:
The present invention is related to a compound represented by formula (I) wherein —X— is —NH— or —S—; —Z— is —O— or —S—; R3, R5 and R6 are each independently a hydrogen atom, substituted or unsubstituted alkyl, or the like; R7 is a cyano, substituted or unsubstituted amino, or the like; R7′ is each independently a halogen; b is 0 or 1; or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising thereof.
Public/Granted literature
- US20160200721A1 AROMATIC HETEROCYCLYLAMINE DERIVATIVE HAVING TRPV4-INHIBITING ACTIVITY Public/Granted day:2016-07-14
Information query
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