Invention Grant
- Patent Title: 4′-azido, 3′-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication
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Application No.: US14366189Application Date: 2012-12-17
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Publication No.: US09708357B2Publication Date: 2017-07-18
- Inventor: Mark Smith , Francisco Xavier Talamas , Jing Zhang , Zhuming Zhang
- Applicant: Riboscience LLC
- Applicant Address: US CA Palo Alto
- Assignee: Riboscience, LLC
- Current Assignee: Riboscience, LLC
- Current Assignee Address: US CA Palo Alto
- Agency: GrayRobinson, P.A.
- Agent Jennifer L. Kisko
- International Application: PCT/EP2012/075688 WO 20121217
- International Announcement: WO2013/092447 WO 20130627
- Main IPC: A61K38/21
- IPC: A61K38/21 ; C12N5/00 ; C12N5/02 ; A61K31/70 ; A01N43/04 ; C07H19/04 ; C07H19/10 ; C07H19/20 ; C07H19/048 ; C07H19/06 ; C07H19/16 ; A61K31/7068 ; A61K31/7072 ; A61K45/06
Abstract:
The present invention relates to the use of 3′-fluoro, 4′-azido nucleoside phosphoramidate prodrug derivatives of formula I wherein the symbols are as defined in the specification, to pharmaceutically acceptable salts thereof, and to pharmaceutical compositions containing such compounds for the treatment of HCV.
Public/Granted literature
- US20140369959A1 4'-AZIDO, 3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION Public/Granted day:2014-12-18
Information query
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