Invention Grant
- Patent Title: Antisense nucleic acids
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Application No.: US14615504Application Date: 2015-02-06
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Publication No.: US09708361B2Publication Date: 2017-07-18
- Inventor: Naoki Watanabe , Youhei Satou , Shin'ichi Takeda , Tetsuya Nagata
- Applicant: NIPPON SHINYAKU CO., LTD. , NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
- Applicant Address: JP Kyoto-shi, Kyoto JP Tokyo
- Assignee: NIPPON SHINYAKU CO., LTD.,NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
- Current Assignee: NIPPON SHINYAKU CO., LTD.,NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
- Current Assignee Address: JP Kyoto-shi, Kyoto JP Tokyo
- Agency: Drinker Biddle & Reath LLP
- Priority: JP2010-196032 20100901
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/70 ; C12N15/11 ; C12N15/113 ; C07H21/00 ; C12N5/00
Abstract:
The present invention provides an oligomer which efficiently enables to cause skipping of the 53rd exon in the human dystrophin gene. Also provided is a pharmaceutical composition which causes skipping of the 53rd exon in the human dystrophin gene with a high efficiency.
Public/Granted literature
- US20150166995A1 ANTISENSE NUCLEIC ACIDS Public/Granted day:2015-06-18
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