Invention Grant
- Patent Title: Purification process for monoclonal antibodies
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Application No.: US14895432Application Date: 2014-06-25
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Publication No.: US09708365B2Publication Date: 2017-07-18
- Inventor: Sanjeev Kumar Mendiratta , Sanjay Bandyopadhyay , Avanish Kumar Singh
- Applicant: Cadila Healthcare Limited
- Applicant Address: IN Ahmedabad Gujarat
- Assignee: Cadila Healthcare Limited
- Current Assignee: Cadila Healthcare Limited
- Current Assignee Address: IN Ahmedabad Gujarat
- Agency: Schwegman Lundberg & Woessner, P.A.
- Priority: IN2145/MUM/2013 20130625
- International Application: PCT/IN2014/000421 WO 20140625
- International Announcement: WO2014/207763 WO 20141231
- Main IPC: C07K1/36
- IPC: C07K1/36 ; C07K1/20 ; C07K1/22 ; C07K16/06 ; C07K16/24 ; C07K16/28 ; C07K16/32

Abstract:
The present invention provides an improved method for the purification of monoclonal antibody from cell culture. Process of purification of the desired monoclonal antibody comprises affinity, hydrophobic interaction and optionally ion exchange column chromatography. It provides more than 99% purity of the desired monoclonal antibody.
Public/Granted literature
- US20160115195A1 PURIFICATION PROCESS FOR MONOCLONAL ANTIBODIES Public/Granted day:2016-04-28
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