Invention Grant
- Patent Title: IL-17A/F cross-reactive monoclonal antibodies and methods of using the same
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Application No.: US14402322Application Date: 2013-05-21
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Publication No.: US09708401B2Publication Date: 2017-07-18
- Inventor: Brenda L. Stevens , Mark W. Rixon , Scott R. Presnell
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Brian J. Walsh
- International Application: PCT/US2013/041928 WO 20130521
- International Announcement: WO2013/177101 WO 20131128
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/24 ; C07K16/46 ; A61K39/00
Abstract:
The present invention relates to antagonizing the activity of IL-17A, IL-17F and IL-23 using bispecific antibodies that comprise a binding entity that is cross-reactive for IL-17A and IL-17F and a binding entity that binds IL-23p19. The present invention relates to novel bispecific antibody formats and methods of using the same.
Public/Granted literature
- US20150086552A1 BISPECIFIC ANTIBODIES AND METHODS OF USING THE SAME Public/Granted day:2015-03-26
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