Invention Grant
- Patent Title: Anti-BAFF-anti-IL-17 bispecific antibodies
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Application No.: US15157782Application Date: 2016-05-18
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Publication No.: US09708402B2Publication Date: 2017-07-18
- Inventor: Barrett Allan , Robert Jan Benschop , Jirong Lu
- Applicant: Eli Lilly and Company
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Megan N. Thobe; Gregory A. Cox
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; A61K39/395 ; A61K39/40 ; C07K16/24 ; C07K16/46 ; C07K16/28 ; C07K1/00

Abstract:
Bispecific antibodies are provided that specifically bind B-cell Activating Factor of the TNF Family (BAFF) and Interleukin-17A (IL-17) and are characterized as having high affinity and strong neutralizing properties to both BAFF and IL-17. The bispecific antibodies of the invention are expected to be useful in treating Lupus Nephritis (LN), Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA), Psoriasis (Ps), Ankylosing Spondylitis (AS), Psoriatic Arthritis (PA), primary Sjögren's Syndrome (pSS), or Multiple Myeloma (MM).
Public/Granted literature
- US20160251430A1 ANTI-BAFF-ANTI-IL-17 BISPECIFIC ANTIBODIES Public/Granted day:2016-09-01
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