Invention Grant
- Patent Title: Treatment of delta-like 1 homolog (DLK1) related diseases by inhibition of natural antisense transcript to DLK1
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Application No.: US13256710Application Date: 2010-03-16
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Publication No.: US09708604B2Publication Date: 2017-07-18
- Inventor: Joseph Collard , Olga Khorkova Sherman , Carlos Coito
- Applicant: Joseph Collard , Olga Khorkova Sherman , Carlos Coito
- Applicant Address: US FL Miami
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Current Assignee Address: US FL Miami
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- International Application: PCT/US2010/027403 WO 20100316
- International Announcement: WO2010/107740 WO 20100923
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; C12N5/00
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Delta-like (1) homolog (DLK1), in particular, by targeting natural antisense polynucleotides of Delta-like (1) homolog (DLK1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of (DLK1).
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