Invention Grant
- Patent Title: Cationic lipid having improved intracellular kinetics
-
Application No.: US14280016Application Date: 2014-05-16
-
Publication No.: US09708628B2Publication Date: 2017-07-18
- Inventor: Kota Tange , Masaya Arai , Kazuhiro Kubo , Hidetaka Akita , Hideyoshi Harashima , Hiroto Hatakeyama , Ryohei Ishiba , Masami Ukawa , Hiroki Tanaka
- Applicant: NOF CORPORATION , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
- Applicant Address: JP Tokyo JP Sapporo
- Assignee: NOF Corporation,National University Corporation Hokkaido University
- Current Assignee: NOF Corporation,National University Corporation Hokkaido University
- Current Assignee Address: JP Tokyo JP Sapporo
- Agency: Leydig, Viot & Mayer, Ltd.
- Priority: JP2011-252309 20111118
- Main IPC: A61K47/20
- IPC: A61K47/20 ; C12N15/88 ; A61K47/22 ; A61K9/127 ; C07C323/25 ; C07D311/72 ; A61K9/00

Abstract:
The present invention relates to a compound represented by the formula (1) wherein Xa and Xb are each independently X1 or X2; s is 1 or 2, R4 is an alkyl group having 1-6 carbon atoms, na and nb are each independently 0 or 1, R1a and R1b are each independently an alkylene group having 1-6 carbon atoms, R2a and R2b are each independently an alkylene group having 1-6 carbon atoms, Ya and Yb are each independently an ester bond, an amide bond, a carbamate bond, an ether bond or a urea bond, and R3a and R3b are each independently a sterol residue, a liposoluble vitamin residue or an aliphatic hydrocarbon group having 12-22 carbon atoms, and use thereof.
Public/Granted literature
- US20140335157A1 CATIONIC LIPID HAVING IMPROVED INTRACELLULAR KINETICS Public/Granted day:2014-11-13
Information query
IPC分类: