Invention Grant
- Patent Title: HiC: method of identifying interactions between genomic loci
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Application No.: US15137988Application Date: 2016-04-25
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Publication No.: US09708648B2Publication Date: 2017-07-18
- Inventor: Job Dekker , Erez Lieberman Aiden , Nynke Van Berkum , Andreas Gnirke , Eric Lander , Chad Nusbaum , Louise Williams , Alexandre Melnikov , Georgia Giannoukos
- Applicant: University of Massachusetts , Massachusetts Institute of Technology , President and Fellows of Harvard College , Whitehead Institute for Biomedical Research
- Applicant Address: US MA Boston US MA Cambridge US MA Cambridge US MA Cambridge
- Assignee: University of Massachusetts,Massachusetts Institute of Technology,President and Fellows of Harvard College,Whitehead Institute for Biomedical Research
- Current Assignee: University of Massachusetts,Massachusetts Institute of Technology,President and Fellows of Harvard College,Whitehead Institute for Biomedical Research
- Current Assignee Address: US MA Boston US MA Cambridge US MA Cambridge US MA Cambridge
- Agency: Medlen & Carroll, LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
Public/Granted literature
- US20160312273A1 HiC: Method of Identifying Interactions Between Genomic Loci Public/Granted day:2016-10-27
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