Invention Grant
- Patent Title: Method and apparatus for tracking cell identity
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Application No.: US14523376Application Date: 2014-10-24
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Publication No.: US09709479B2Publication Date: 2017-07-18
- Inventor: Marc Castellarnau , Gregory Lee Szeto , Darrell J. Irvine , John Christopher Love , Joel Voldman
- Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Applicant Address: US MA Cambridge
- Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Current Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Current Assignee Address: US MA Cambridge
- Agency: Steptoe & Johnson LLP
- Main IPC: G01N15/10
- IPC: G01N15/10 ; G01N15/14 ; G01N35/00 ; G01N15/00

Abstract:
A method of tracking cell identity across analytical platforms uses stochastic barcoding (SB). SB uses a randomly generated code based on one or more of the number, color and position of beads encapsulated together with a set of cells of interest. SB use is demonstrated in an application where cells are transferred from a microwell array into a microtiter plate while keeping their identity, and obtained an average identification accuracy of 96% for transfer of 100 blocks. Model scaling of the method up to 1000 blocks demonstrated that SB is able to achieve approximately 90% accuracy.
Public/Granted literature
- US20150253237A1 METHOD AND APPARATUS FOR TRACKING CELL IDENTITY Public/Granted day:2015-09-10
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