A method for isolating a potential anomaly in imaging data comprising: providing a set of at least one given anomaly property representative of a given anomaly; providing a anomaly property identifier for identifying each of the at least one given anomaly property; in the imaging data, isolating a first zone having a first property and a group of at least one other zone, each of the at least one other zone having a corresponding property different than the first property; in the imaging data, and resulting from the isolation of a first zone and a group of at least one other zone, providing a transition zone selected from a group consisting of: a closed zone separating the first zone and the group of at least one other zone; and a closed zone extending in one of the first zone and the group of at least one other zone; applying the anomaly property identifier for identifying each of the at least one given anomaly property on at least the transition zone for providing a computed indication for a selected zone, the selected zone being at least the transition zone; determining if the computed indication for the selected zone is concording with each of the at least one given anomaly property; and if the computed indication for the selected zone is concording, assigning an indication of potential anomaly candidate zone to the selected zone to thereby isolate the potential anomaly.