Systems and methods for decoding neural and/or electromyographic signals are provided. A system can include at least one single channel decoder. Optionally, the system can include a demixer in operable communication with the single channel decoders. Each single channel decoder can include a filter to attenuate noise and sharpen spikes in the neural and/or electromyographic signals, a detection function to identify spikes, and a demodulator to get a real-time estimate of motor intent.