Invention Grant
- Patent Title: Oxysterol analogue OXY133 induces osteogenesis and hedgehog signaling and inhibits adipogenesis
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Application No.: US14399121Application Date: 2013-03-15
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Publication No.: US09717742B2Publication Date: 2017-08-01
- Inventor: Farhad Parhami , Michael E. Jung , Frank Stappenbeck
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- International Application: PCT/US2013/032693 WO 20130315
- International Announcement: WO2013/169399 WO 20131114
- Main IPC: A61K31/575
- IPC: A61K31/575 ; A61K35/32 ; A61K38/18 ; A61K38/30 ; A61K45/06 ; C07J9/00 ; C07J51/00
Abstract:
This invention relates, e.g., to a synthetic compound, Oxy133, having the structure [Formula I] or a bioactive or pharmaceutical composition comprising Oxy133 and a pharmaceutically acceptable carrier. Methods are also disclosed for using the compound or bioactive or pharmaceutical composition to treat a variety of disorders, including e.g. bone disorders, obesity, cardiovascular disorders, and neurological disorders.
Public/Granted literature
- US20150118277A1 OXYSTEROL ANALOGUE OXY133 INDUCES OSTEOGENESIS AND HEDGEHOG SIGNALING AND INHIBITS ADIPOGENESIS Public/Granted day:2015-04-30
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