Invention Grant
- Patent Title: Microvesicles (MVS) derived from adult stem cells for use in the therapeutic treatment of a tumor disease
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Application No.: US13581537Application Date: 2011-02-28
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Publication No.: US09717760B2Publication Date: 2017-08-01
- Inventor: Stefania Bruno , Maria Beatriz Herrera Sanchez , Valentina Fonsato , Giovanni Camussi , Ciro Tetta
- Applicant: Stefania Bruno , Maria Beatriz Herrera Sanchez , Valentina Fonsato , Giovanni Camussi , Ciro Tetta
- Applicant Address: DE Bad Homburg
- Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
- Current Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
- Current Assignee Address: DE Bad Homburg
- Agency: Jacobson Holman, PLLC.
- Priority: EP10425052 20100302
- International Application: PCT/EP2011/052945 WO 20110228
- International Announcement: WO2011/107437 WO 20110909
- Main IPC: A61K35/407
- IPC: A61K35/407 ; A61K31/00 ; C12N5/00 ; C12N5/02 ; A61K35/28
Abstract:
The invention is in the field of therapeutic treatment of tumors. The inventors have found that microvesicles derived from adult stem cells exert a remarkable anti-tumor effect when administered to a patient affected by a tumor disease. Preferred microvesicles are derived from a bone marrow-mesenchymal stem cell, a glomerular mesenchymal stem cell or a non-oval liver stem cell.
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