A centrifuge drive head for releasably connecting a driving system to a rotor of a centrifuge. The centrifuge drive head comprises a base body mounted for rotation about an axis of rotation (R) and at least a first and a second coupling element, mounted on the base body for swinging outwardly about a swivel axis. The first and second coupling elements differ from each other in at least one of outer shape, mass, material and/or mounting height on the base body.