A liquid discharge apparatus includes a head, a head holder, a carriage, a supply tube, a reference member, a first guide, and a second guide. The supply tube is led out from the carriage and extended to a first side of the head holder opposite a second side of the head holder at which the head holder is hooked on the reference member. The supply tube is disposed in a state in which, in plan view, the supply tube projects from an entry portion of the second guide beyond an end of the head holder in a main scanning direction. At least a portion of the first guide to guide the supply tube is disposed closer to the head holder, in plan view, than a position at which the supply tube projects farthest beyond the end of the head holder in the main scanning direction.