Invention Grant
- Patent Title: Substituted pyridines as sodium channel blockers
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Application No.: US14961026Application Date: 2015-12-07
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Publication No.: US09718780B2Publication Date: 2017-08-01
- Inventor: Laykea Tafesse , Jiangchao Yao
- Applicant: Purdue Pharma L.P.
- Agency: Purdue Pharma L.P.
- Agent Alan L. Koller; Weiying Yang
- Main IPC: C07D213/24
- IPC: C07D213/24 ; C07D239/24 ; A61K31/47 ; A61K31/505 ; C07D213/50 ; C07D213/81 ; C07D213/30 ; C07D213/46 ; C07D213/56 ; C07D213/57
Abstract:
The invention relates to substituted pyridine and pyrimidine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1, R2a, R2b, A1, A2, X, and Z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
Public/Granted literature
- US20160145210A1 SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS Public/Granted day:2016-05-26
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