Invention Grant
- Patent Title: Poly (ADP-ribose) polymerase inhibitor
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Application No.: US14826181Application Date: 2015-08-13
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Publication No.: US09718787B2Publication Date: 2017-08-01
- Inventor: Jianxin Ji , Na Guo , Ting Xue , Bingqiang Kang , Xinfa Ye , Xin Chen , Tao Zhang
- Applicant: CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD.
- Applicant Address: CN High Tech Development Zone, Chengdu
- Assignee: CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD.
- Current Assignee: CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD.
- Current Assignee Address: CN High Tech Development Zone, Chengdu
- Agency: Jun He Law Offices P.C.
- Agent James J. Zhu
- Priority: CN201110390364 20111130
- Main IPC: C07D237/32
- IPC: C07D237/32 ; C07D401/12 ; C07D403/12 ; C07D413/12 ; C07D417/12 ; C07D409/12 ; C07D405/12
Abstract:
Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like.
Public/Granted literature
- US20150368205A1 POLY (ADP-RIBOSE) POLYMERASE INHIBITOR Public/Granted day:2015-12-24
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