Invention Grant
- Patent Title: Substituted benzoazepines as toll-like receptor modulators
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Application No.: US13979632Application Date: 2012-01-12
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Publication No.: US09718796B2Publication Date: 2017-08-01
- Inventor: James Jeffry Howbert , Robert Hershberg , Laurence E. Burgess , Hong Woon Yang
- Applicant: James Jeffry Howbert , Robert Hershberg , Laurence E. Burgess , Hong Woon Yang
- Applicant Address: US WA Seattle US CO Boulder
- Assignee: VENTIRX PHARMACEUTICALS, INC.,ARRAY BIOPHARMA, INC.
- Current Assignee: VENTIRX PHARMACEUTICALS, INC.,ARRAY BIOPHARMA, INC.
- Current Assignee Address: US WA Seattle US CO Boulder
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2012/021110 WO 20120112
- International Announcement: WO2012/097173 WO 20120719
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D223/16 ; C07D401/04 ; C07D401/14 ; C07D403/06 ; C07D403/10 ; C07D413/10 ; C07D295/192 ; C07D487/04
Abstract:
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.
Public/Granted literature
- US20140066432A1 Substituted Benzoazepines As Toll-Like Receptor Modulators Public/Granted day:2014-03-06
Information query
