Invention Grant
- Patent Title: 2, 6-Di-nitrogen-containing substituted purine derivative, and preparation method, pharmaceutical composition and use thereof
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Application No.: US14914674Application Date: 2014-08-27
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Publication No.: US09718823B2Publication Date: 2017-08-01
- Inventor: Guofeng Wu , Yongmei Xu , Wei Mao , Chunlin Chen , Zhanggui Wu , Xiaoqin Lin , Jun Wang , Jinna Cai , Sen Xiao , Lili Lv
- Applicant: Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
- Applicant Address: CN Xinchang County
- Assignee: ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY
- Current Assignee: ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY
- Current Assignee Address: CN Xinchang County
- Agency: Lipton, Weinberger & Husick
- Agent Ash Tankha
- Priority: CN201310388308 20130830; CN201410417725 20140822
- International Application: PCT/CN2014/000799 WO 20140827
- International Announcement: WO2015/027667 WO 20150305
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/52 ; C07D473/00 ; C07D473/18 ; A61K31/5377 ; C07D473/16
Abstract:
The present invention provides a 2, 6-di-nitrogen-containing substituted purine derivative having a formula (I) structure, or pharmaceutical salt or hydrate thereof, and preparation method and use thereof. The compound is broad spectrum anticancer, low toxicity, high anticancer activity and good stability.
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