Invention Grant
- Patent Title: Artificial antigen of aflatoxin biosynthetic precursor sterigmatocystin and method for preparing same
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Application No.: US14667341Application Date: 2015-03-24
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Publication No.: US09718836B2Publication Date: 2017-08-01
- Inventor: Peiwu Li , Qi Zhang , Min Li , Fei Ma , Xiaoxia Ding
- Applicant: OILCROPS RESEARCH INSTITUTE OF CHINESE ACADEMY OF AGRICULTURE SCIENCES
- Applicant Address: CN Wuhan, Hubei
- Assignee: OILCROPS RESEARCH INSTITUTE OF CHINESE ACADEMY OF AGRICULTURE SCIENCES
- Current Assignee: OILCROPS RESEARCH INSTITUTE OF CHINESE ACADEMY OF AGRICULTURE SCIENCES
- Current Assignee Address: CN Wuhan, Hubei
- Agency: Locke Lord LLP
- Agent Tim Tingkang Xia, Esq.
- Priority: CN201410115645 20140326
- Main IPC: A61K39/02
- IPC: A61K39/02 ; A61K39/00 ; A61K39/385 ; C07D493/14 ; A61K31/335
Abstract:
An artificial antigen of aflatoxin biosynthetic precursor Sterigmatocystin (ST) and a method for preparing same. Firstly, hydroxyacetic acid is reacted with the double bound of the difuran ring in the aflatoxin biosynthetic precursor ST, yielding an aflatoxin biosynthetic precursor ST hapten with an active carboxymethoxy group. Secondly, a carboxyl group on the ST hapten is attached to an amino group on a carrier protein. At last, the artificial antigen of aflatoxin biosynthetic precursor ST is obtained by dialysis and lyophilize.
Public/Granted literature
- US20150274846A1 ARTIFICIAL ANTIGEN OF AFLATOXIN BIOSYNTHETIC PRECURSOR STERIGMATOCYSTIN AND METHOD FOR PREPARING SAME Public/Granted day:2015-10-01
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