Invention Grant
- Patent Title: Condensed 5-oxazolidinone derivative
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Application No.: US15110811Application Date: 2014-09-12
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Publication No.: US09718840B2Publication Date: 2017-08-01
- Inventor: Yohei Ikuma , Masato Iwata , Chongkwang Lee
- Applicant: SUMITOMO DAINIPPON PHARMA CO., LTD.
- Applicant Address: JP Osaka-shi
- Assignee: SUMITOMO DAINIPPON PHARMA CO., LTD.
- Current Assignee: SUMITOMO DAINIPPON PHARMA CO., LTD.
- Current Assignee Address: JP Osaka-shi
- Agency: Sughrue Mion, PLLC
- Priority: JP2014-004252 20140114
- International Application: PCT/JP2014/074768 WO 20140912
- International Announcement: WO2015/107724 WO 20150723
- Main IPC: C07D498/04
- IPC: C07D498/04 ; A61K31/424 ; A61K31/454 ; A61K45/06 ; A61K31/404 ; C07B59/00 ; C07D401/14 ; C07D403/12 ; C12P17/16 ; C12P17/18

Abstract:
Provided are condensed 5-oxazolidinone derivatives and pharmaceutically permissible salts thereof, which have excellent anticoagulant effects, are well absorbed orally, and are useful as therapeutic drugs for thrombosis, etc. Compounds represented by formula (1) and pharmaceutically permissible salts thereof. [In the formula, L represents a C1-C4 alkylene group that may be substituted; R11 and R12 each independently represent a hydrogen atom or C1-C6 alkyl group, etc. that may be substituted; X1 represents N or CR1; R1 and R2 each independently represent a hydrogen atom, halogen atom, or C1-C6 alkyl group; Ra represents a C4-C7 cycloalkyl group, etc. that may be substituted; and Rb represents a hydrogen atom, etc.]
Public/Granted literature
- US20170022218A1 CONDENSED 5-OXAZOLIDINONE DERIVATIVE Public/Granted day:2017-01-26
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