Invention Grant
- Patent Title: Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof
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Application No.: US13147193Application Date: 2010-02-06
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Publication No.: US09718863B2Publication Date: 2017-08-01
- Inventor: Stefano Colloca , Alfredo Nicosia , Riccardo Cortese , Virginia Ammendola , Maria Ambrosio
- Applicant: Stefano Colloca , Alfredo Nicosia , Riccardo Cortese , Virginia Ammendola , Maria Ambrosio
- Applicant Address: BE
- Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee Address: BE
- Agent Lisa M. Matovcik; Virginia Campen
- Priority: WOPCT/EP2009/000672 20090202
- International Application: PCT/EP2010/000616 WO 20100206
- International Announcement: WO2010/086189 WO 20100805
- Main IPC: C07K14/005
- IPC: C07K14/005 ; A61K39/12 ; A61K39/235 ; C12N7/00 ; C12N15/861 ; C12N15/86 ; A61K39/00 ; A61K48/00
Abstract:
The present invention relates to novel adenovirus strains with an improved seroprevalence. In one aspect, the present invention relates to isolated polypeptides of adenoviral capsid proteins such as hexon, penton and fiber protein and fragments thereof and polynucleotides encoding the same. Also provided is a vector comprising the isolated polynucleotide according to the invention and adenoviruses comprising the isolated polynucleotides or polypeptides according to the invention and a pharmaceutical composition comprising said vector, adenovirus, polypeptide and/or polynucleotide. The invention also relates to the use of the isolated polynucleotides, the isolated polypeptides, the vector, the adenoviruses and/or the pharmaceutical composition for the therapy or prophylaxis of a disease.
Public/Granted literature
- US20120027788A1 SIMIAN ADENOVIRUS NUCLEIC ACID- AND AMINO ACID-SEQUENCES, VECTORS CONTAINING SAME, AND USES THEREOF Public/Granted day:2012-02-02
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