Invention Grant
- Patent Title: GDF-5 mutant for inducing cartilage formation
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Application No.: US14362691Application Date: 2012-12-05
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Publication No.: US09718867B2Publication Date: 2017-08-01
- Inventor: Frank Plöger , Florian Wagner
- Applicant: BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH
- Applicant Address: DE Heidelberg
- Assignee: BIOPHARMA GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH
- Current Assignee: BIOPHARMA GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH
- Current Assignee Address: DE Heidelberg
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: EP11191973 20111205
- International Application: PCT/EP2012/074549 WO 20121205
- International Announcement: WO2013/083649 WO 20130613
- Main IPC: C07K14/51
- IPC: C07K14/51 ; C07K14/495
Abstract:
The present invention is directed to GDF-5 related proteins having an improved capability of inducing cartilage formation and a reduced capability of inducing bone formation. The novel proteins are particularly useful in the treatment of cartilage defects, wherein the formation of bone tissue is undesirable.
Public/Granted literature
- US20140369978A1 GDF-5 MUTANT FOR INDUCING CARTILAGE FORMATION Public/Granted day:2014-12-18
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