Invention Grant
- Patent Title: Monoclonal antibodies with enhanced ADCC function
-
Application No.: US14676508Application Date: 2015-04-01
-
Publication No.: US09718890B2Publication Date: 2017-08-01
- Inventor: Roland Beliard , Dominique Bourel , Arnaud Glacet , Christophe De Romeuf , Nicolas Bihoreau , Emmanuel Nony
- Applicant: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES
- Applicant Address: FR Les Ulis
- Assignee: Laboratoire Francais Du Fractionnement Et Des Biotechnologies
- Current Assignee: Laboratoire Francais Du Fractionnement Et Des Biotechnologies
- Current Assignee Address: FR Les Ulis
- Agency: Potomac Law Group PLLC
- Agent Rouget F. Henschel
- Priority: FR0004685 20000412
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K16/34 ; A61K39/00
Abstract:
The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADCC-type test, said antibodies capable of activating type III Fcy receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunization in Rh negative persons, in particular for hemolytic disease in a new-born baby or for uses such as idiopathic thrombocytopenic purpura (ITP).
Public/Granted literature
- US20150266972A1 MONOCLONAL ANTIBODIES WITH ENHANCED ADCC FUNCTION Public/Granted day:2015-09-24
Information query
IPC分类:
