Invention Grant
- Patent Title: Genomics of actinoplanes utahensis
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Application No.: US13814235Application Date: 2011-08-01
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Publication No.: US09719064B2Publication Date: 2017-08-01
- Inventor: Klaus Selber , Bernhard Weingaertner , Hermann Wehlmann , Winfried Rosen , Alfred Pühler , Patrick Schwientek , Jörn Kalinowski , Udo Wehmeier
- Applicant: Klaus Selber , Bernhard Weingaertner , Hermann Wehlmann , Winfried Rosen , Alfred Pühler , Patrick Schwientek , Jörn Kalinowski , Udo Wehmeier
- Applicant Address: DE Monheim
- Assignee: BAYER INTELLECTUAL PROPERTY GMBH
- Current Assignee: BAYER INTELLECTUAL PROPERTY GMBH
- Current Assignee Address: DE Monheim
- Agency: Morrison & Foerster LLP
- Priority: EP10171831 20100804
- International Application: PCT/EP2011/063243 WO 20110801
- International Announcement: WO2012/016960 WO 20120209
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C07K14/365 ; C12P19/26

Abstract:
The present invention describes the DNA-sequence of the wild type genome as well as all genetic modifications which were introduced into the wild type—and further developed strains, based thereon. Thereby the first genotypic characterization of the developed strains, including the latest production strain, has been accomplished, accounting for the major part of the invention. Furthermore, on the basis of the determined DNA-sequences, potential genes were identified and account, combined with their functional annotation, for another part of the invention. In particular, the gene- and DNA-sequences, as well as protein-sequences derived there out, contribute to the invention which were affected by mutagenic modifications throughout the strain development process, potentially contributing to the increased production yield.
Public/Granted literature
- US20130302855A1 GENOMICS OF ACTINOPLANES UTAHENSIS Public/Granted day:2013-11-14
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