Chemical exchange saturation transfer (CEST) effects are enhanced by forming, for each of a plurality of magnetization transfer (MT) offset frequencies within a specified first range, a respective image representing CEST effects. A subset of the formed CEST images is displayed and a preferred or optimum one is selected from a display screen. The thus identified target frequency is then used to generate a composite enhanced CEST image based upon a combination of formed CEST images having MT frequencies within a specified second, smaller range, around the identified target frequency.