The present invention provides a touch signal detection circuit. The touch signal detection circuit includes: a processing unit, at least one linear transmitting electrode, and at least two linear receiving electrodes; the transmitting electrode is perpendicular to the receiving electrode, the receiving electrode is perpendicular to a source driver line of a display screen, and each receiving electrode and each transmitting electrode form one node mutual capacitance; the processing unit acquires capacitance change values of at least two node mutual capacitances, and acquires a location of a touch signal according to the capacitance change values of the at least two node mutual capacitances.