Methods and apparatuses are provided for a User Equipment (UE) to transmit an acknowledgement signal over multiple Transmission Time Intervals (TTIs). The method includes transmitting the acknowledgement signal in {(n+Q)th, (n+Q+1)th, . . . , (n+Q+N−1)th} Transmission Time Intervals (TTIs), the acknowledgement signal corresponding to a data packet the UE receives in an nth TTI; and not transmitting a non-acknowledgement signal in the {(n+Q)th, (n+Q+1)th, . . . , (n+Q+N−1)th} TTIs. n is an integer, Q is a number greater than 0, and N is a number greater than 1.