A biopsy device may comprise a probe assembly that has a needle assembly extending distally from the probe assembly. The needle assembly has a needle portion and blade assembly. The blade assembly comprises a blade and a multi-member coupling assembly. The multi-member coupling assembly is configured to couple to the blade and to the needle portion to attach the blade to the needle portion. In one configuration the multi-member coupling assembly comprises two coupling members configure to couple to the blade. The blade may be a flat blade that has a retention channel formed therein, wherein the two coupling members may couple to the blade at the retention channel. The needle portion may comprise a needle and a cutter receiving tube. The needle may be an ovular cross-sectioned tube having a cut-out portion into which a circular cross-sectioned cutter receiving tube may be inserted and coupled thereto.