Invention Grant
- Patent Title: γ-aminobutyric acid (GABA) analogues for the treatment of pain and other disorders
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Application No.: US15359120Application Date: 2016-11-22
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Publication No.: US09750720B2Publication Date: 2017-09-05
- Inventor: Premji Meghani , Franz Kricek
- Applicant: Novassay S.A.
- Applicant Address: CH Epalinges
- Assignee: Novassay, S.A.
- Current Assignee: Novassay, S.A.
- Current Assignee Address: CH Epalinges
- Agent Matthew Karer; Adam Warwick Bell
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K31/4245 ; C07D257/04 ; C07D271/07 ; C07C259/14 ; C07C205/50 ; C07C233/10 ; C07C255/31

Abstract:
A compound of Formula 1 wherein R1 represents hydrogen, halo, a C1-C4 alkyl group, a C1-C4 alkylhalide group, a C1-C4 alkoxy-C2-C4 alkyl group, a C2-C4 alkenyl group, a C2-C4 alkynyl group or a C3-C7 cycloalkyl group; R2 represents or a tautomer thereof; and R3 represents hydrogen, a C1-C4 alkyl group, a C1-C4 alkoxy-C2-C4 alkyl group or a C3-C7 cycloalkyl group; or a pharmaceutically acceptable salt or solvate thereof. Processes to prepare said compounds and novel intermediates are also claimed. Such compound finds utility in treating neuropathic pain and disorders of the central nervous system.
Public/Granted literature
- US20170071909A1 NOVEL GAMMA-AMINOBUTYRIC ACID (GABA) ANALOGUES FOR THE TREATMENT OF PAIN AND OTHER DISORDERS Public/Granted day:2017-03-16
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