Invention Grant
- Patent Title: Diazole amides
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Application No.: US14878784Application Date: 2015-10-08
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Publication No.: US09750722B2Publication Date: 2017-09-05
- Inventor: Xi Chen , Dean R. Dragoli , Pingchen Fan , Juan C. Jaen , Yandong Li , Jay P. Powers , Viengkham Malathong , Sreenivas Punna , Hiroko Tanaka , Penglie Zhang
- Applicant: ChemoCentryx, Inc.
- Applicant Address: US CA Mountain View
- Assignee: CHEMOCENTRYX, INC.
- Current Assignee: CHEMOCENTRYX, INC.
- Current Assignee Address: US CA Mountain View
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo PC
- Main IPC: C07D233/88
- IPC: C07D233/88 ; A61K31/437 ; A61K31/4178 ; A61K45/06 ; C07D401/12 ; A61K31/4155 ; C07D231/40 ; A61K31/4192 ; A61K31/4196 ; C07D471/04 ; C07D403/12
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
Public/Granted literature
- US20160193185A1 DIAZOLE AMIDES Public/Granted day:2016-07-07
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