Invention Grant
- Patent Title: METAP2 inhibitors and methods of treating obesity
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Application No.: US15226258Application Date: 2016-08-02
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Publication No.: US09750737B2Publication Date: 2017-09-05
- Inventor: John S. Petersen , James Shanahan
- Applicant: SynDevRx, Inc.
- Applicant Address: US MA Cambridge
- Assignee: SynDevRx, Inc.
- Current Assignee: SynDevRx, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Cooley LLP
- Agent Ivor R. Elrifi; Matthew Pavao
- Main IPC: A61K31/77
- IPC: A61K31/77 ; A61K31/485 ; A61K47/48 ; A61K31/336 ; A61K38/06
Abstract:
The present invention relates to modified or polymer conjugated MetAP2 inhibitors. The present invention also relates to methods of preventing, inducing, causing or increasing weight loss, treating obesity and/or treating metabolic syndrome utilizing the modified or polymer conjugated MetAP2 inhibitors. The present invention also relates to methods of improving insulin sensitivity and glycemic control, reducing insulin levels and/or improving leptin sensitivity utilizing the modified or polymer conjugated MetAP2 inhibitors.
Public/Granted literature
- US20160346244A1 METAP2 INHIBITORS AND METHODS OF TREATING OBESITY Public/Granted day:2016-12-01
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