Invention Grant
- Patent Title: Multifunctional oral vaccine based on chromosome recombineering
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Application No.: US14428870Application Date: 2013-09-16
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Publication No.: US09750793B2Publication Date: 2017-09-05
- Inventor: Madushini Nirosha Dharmasena , Dennis J. Kopecko
- Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
- Applicant Address: US DC Washington
- Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2013/059980 WO 20130916
- International Announcement: WO2014/043637 WO 20140320
- Main IPC: A61K39/112
- IPC: A61K39/112 ; C07H21/02 ; A61K39/00 ; C07K14/25 ; C07K14/255 ; C12N1/20
Abstract:
A recombineered Salmonella typhi Ty21a, compositions and vaccines comprising such a Ty21a, and a method for recombineering comprising inserting a large antigenic region into a bacterial chromosome for the purpose of making multivalent vaccines to protect against one or more disease agents are described herein.
Public/Granted literature
- US20150238591A1 Multifunctional Oral Vaccine Based on Chromosome Recombineering Public/Granted day:2015-08-27
Information query
