Invention Grant
- Patent Title: Combination of local and systemic immunomodulative therapies for melanoma and liver cancer
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Application No.: US14748634Application Date: 2015-06-24
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Publication No.: US09750807B2Publication Date: 2017-09-05
- Inventor: Craig J. Eagle , H. Craig Dees , Eric A. Wachter , Jamie Singer
- Applicant: Provectus Pharmaceuticals, Inc. , Pfizer, Inc.
- Applicant Address: US TN Knoxville US NY New York
- Assignee: Provectus Pharmatech, Inc.,Pfizer, Inc.
- Current Assignee: Provectus Pharmatech, Inc.,Pfizer, Inc.
- Current Assignee Address: US TN Knoxville US NY New York
- Agency: Husch Blackwell LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/352 ; A61K38/21 ; C07K16/30 ; A61K38/19 ; A61K38/20 ; A61K47/48 ; A61K31/365 ; A61K39/245 ; A61K47/02 ; C12N7/00 ; A61K45/06 ; A61K39/00
Abstract:
A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition, in combination with a therapeutically effective amount of a systemic immunomodulatory anticancer agent. A further method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition, in combination with a therapeutically effective amount of a systemic targeted anticancer agent. The present invention is further directed to pharmaceutical compositions for treatment of cancer. The intralesional chemoablative pharmaceutical composition can comprise an IL chemoablative agent comprising primarily a halogenated xanthene.
Public/Granted literature
- US09808524B2 Combination of local and systemic immunomodulative therapies for melanoma and liver cancer Public/Granted day:2017-11-07
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