Invention Grant
- Patent Title: Near-infrared dye-conjugated hyaluronic acid derivative and contrast agent for optical imaging including them
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Application No.: US14767362Application Date: 2014-02-21
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Publication No.: US09750827B2Publication Date: 2017-09-05
- Inventor: Koji Miki , Tatsuhiro Inoue , Yasuhito Kobayashi , Katsuya Nakano , Kouichi Ohe , Fumio Yamauchi , Tetsuya Yano , Masato Minami
- Applicant: CANON KABUSHIKI KAISHA
- Applicant Address: JP Tokyo
- Assignee: CANON KABUSHIKI KAISHA
- Current Assignee: CANON KABUSHIKI KAISHA
- Current Assignee Address: JP Tokyo
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Priority: JP2013-033633 20130222
- International Application: PCT/JP2014/054990 WO 20140221
- International Announcement: WO2014/129674 WO 20140828
- Main IPC: A61K8/00
- IPC: A61K8/00 ; A61K49/22 ; C08B37/08 ; A61K47/48
Abstract:
Provided is a compound having a high ICG content that has high accumulation property in a tumor and has a large intensity of a photoacoustic signal emitted from the tumor even when a time period elapses after administration. Specifically, provided is a hyaluronic acid derivative to which polyethylene glycol and an ICG derivative are conjugated.
Public/Granted literature
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