Haemostatic patch and method of preparation
Abstract:
The present invention relates to a haemostatic patch comprising a porous layer based on oxidized cellulose and a neutralized film based on chitosan, said film comprising a free face and a face fixed on one of the faces of the porous layer, and to the method of preparing said patch comprising the following steps: —a°) preparing a porous layer based on oxidized cellulose, —b°) preparing a film based on chitosan starting from an acidic aqueous solution of chitosan, —c°) fixing the film obtained in b°) on one face of the porous layer, —d°) neutralizing the film obtained in b°), —where step c°) can be carried out before or after step d°), characterized in that: the neutralizing step d°) comprises treatment of said film with a neutralizing composition comprising at least ethanol and ammonium hydroxide (NH4OH).
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