Invention Grant
- Patent Title: Biodegradable medical adhesive and preparation method and use thereof
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Application No.: US14355827Application Date: 2012-10-31
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Publication No.: US09750841B2Publication Date: 2017-09-05
- Inventor: Keliang Liu , Liang Xu , Qingsong Zhang , Dazhen Cai , Qingbin Meng
- Applicant: INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. , CHENGDU YIPING MEDICAL SCIENCE & TECHNOLOGY CO., LTD.
- Applicant Address: CN Beijing CN Chengdu
- Assignee: INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A.,CHENGDU YIPING MEDICAL SCIENCE & TECHNOLOGY CO. LTD
- Current Assignee: INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A.,CHENGDU YIPING MEDICAL SCIENCE & TECHNOLOGY CO. LTD
- Current Assignee Address: CN Beijing CN Chengdu
- Agency: Banner & Witcoff, Ltd.
- Priority: CN201110340675 20111102
- International Application: PCT/CN2012/083787 WO 20121031
- International Announcement: WO2013/064059 WO 20130510
- Main IPC: A61L24/06
- IPC: A61L24/06 ; C08F28/02 ; A61L24/00 ; C08F222/32 ; C09J4/00 ; A61L24/04 ; C09J133/14 ; C08F283/02 ; C09J133/20

Abstract:
A medical adhesive with good biodegradable performance capable of undergoing crosslinking copolymerization, comprising a mono-alpha-cyanoacrylate and a bis-alpha-cyanoacrylic acid diol ester monomer molecule. The olefinic bonds in the mono-alpha-cyanoacrylate structure are polymerized in the presence of infinitesimal anions to form a solid 3D high polymer; the 3D high polymer is provided with degradation sites on the web-like backbone chain, with clear degradation path and absorbable degradation products. The medical adhesive can be used for wound adhesive, large area wound hemostasia, and visceral and soft tissue wound closure.
Public/Granted literature
- US20140369952A1 BIODEGRADABLE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Public/Granted day:2014-12-18
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