A handheld antiseptic dispensing applicator device having a reservoir for storing an antiseptic agent, the reservoir being coupled to an applicator pad, and a defeatable membrane or barrier being interposed between the reservoir and the applicator pad. Embodiments of the device comprise a squeezable reservoir, wherein the internal hydraulic pressure of the squeezable reservoir is increased via user applied forces to thereby defeat the membrane releasing the antiseptic agent contained therein which is then absorbed by the applicator pad. The defeatable barrier or membrane is also removable or may be defeated in connection with other mechanisms according to various embodiments.