A saddle ride type vehicle that may include an engine supporting structure and an engine including a crankcase portion and a cylinder portion. The engine may be supported in a lower portion of the vehicle body frame by a front upper hanger portion and a front lower hanger portion. The front upper hanger portion, the front lower hanger portion, and a pivot supporting hole portion may be high-rigidity hangers having high rigidity, and the engine may be supported in the vehicle body frame by a rear lower hanger portion, a rear upper hanger portion, and a cylinder portion hanger portion having low rigidity which portions are provided between the high-rigidity hangers along the frame bodies.