- Patent Title: Tetrahydroquinoline derivatives and their use as Epac inhibitors
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Application No.: US14432768Application Date: 2013-09-17
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Publication No.: US09751838B2Publication Date: 2017-09-05
- Inventor: Frank Lezoualc'h , Rodolphe Fischmeister , Malik Bisserier , Pascal Bouyssou , Jean-Paul Blondeau , Delphine Courilleau
- Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , UNIVERSITE PAUL SABATIER TOULOUSE III , UNIVERSITE PARIS-SUD , UNIVERSITE D'ORLEANS
- Applicant Address: FR Paris FR Toulouse FR Orsay FR Orleans
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM),Universite Paul Sabatier Toulouse III,Universite Paris-Sud,Universite d'Orleans
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM),Universite Paul Sabatier Toulouse III,Universite Paris-Sud,Universite d'Orleans
- Current Assignee Address: FR Paris FR Toulouse FR Orsay FR Orleans
- Agency: Whitham Curtis & Cook, PC
- Priority: EP12306201 20121002
- International Application: PCT/EP2013/069298 WO 20130917
- International Announcement: WO2014/053315 WO 20140410
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/47 ; C07D215/14 ; C07D215/08 ; C07D215/18
Abstract:
The invention relates to tetrahydroquinoline derivatives and their use in the treatment and/or the prevention of a disease wherein the Epac protein is involved, such as inflammation, cancer, vascular diseases, kidney diseases, cognitive disorders and cardiac diseases.
Public/Granted literature
- US20150252002A1 TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS EPAC INHIBITORS Public/Granted day:2015-09-10
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