Invention Grant
- Patent Title: Heteroaryls and uses thereof
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Application No.: US15347334Application Date: 2016-11-09
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Publication No.: US09751854B2Publication Date: 2017-09-05
- Inventor: Indu T. Bharathan , Chris Blackburn , Jeffrey P. Ciavarri , Jouhara Chouitar , Courtney A. Cullis , Natalie D'Amore , Paul E. Fleming , Kenneth M. Gigstad , Krista E. Gipson , Mario Girard , Yongbo Hu , Janice Lee , Gang Li , Mansoureh Rezaei , Michael D. Sintchak , Francois Soucy , Stephen G. Stroud , Tricia J. Vos , Tzu-Tshin Wong , He Xu , Tianlin Xu , Yingchun Ye
- Applicant: Millennium Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Sterne Kessler Goldstein & Fox P.L.L.C.
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D513/04 ; A61K31/444 ; A61K45/06 ; C07D417/14 ; C07D401/14 ; A61K31/506 ; C07D471/04 ; A61K31/437 ; A61K31/549 ; A61K31/497

Abstract:
The present invention provides a compound of formula I: and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
Public/Granted literature
- US20170073326A1 HETEROARYLS AND USES THEREOF Public/Granted day:2017-03-16
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