Invention Grant
- Patent Title: Ethynyl derivatives
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Application No.: US15489295Application Date: 2017-04-17
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Publication No.: US09751856B2Publication Date: 2017-09-05
- Inventor: Georg Jaeschke , Lothar Lindemann , Rainer E. Martin , Antonio Ricci , Daniel Rueher , Heinz Stadler , Eric Vieira
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: HOFFMANN-LA ROCHE INC.
- Current Assignee: HOFFMANN-LA ROCHE INC.
- Current Assignee Address: US NJ Little Falls
- Agent Tamara A. Kale
- Priority: EP13175535 20130708
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D401/04
Abstract:
The present invention relates to ethynyl derivatives as metabotropic glutamate receptor antagonists (negative allosteric modulators) for use in the treatment of, e.g., anxiety and pain, depression, Fragile-X syndrome, autism spectrum disorders, Parkinson's disease, and gastroesophageal reflux disease (GERD).
Public/Granted literature
- US20170217926A1 ETHYNYL DERIVATIVES Public/Granted day:2017-08-03
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